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RAMOS

RAMOS determines the oxygen transfer rate (OTR), the carbon dioxide transfer rate (CTR) and the respiratory quotient (RQ) of microbial, plantal and cell cultures online. The respiration rates (OTR, CTR) are the most suitable measurable variables to quantify the physiological state of fermented cultures.

RAMOS is the right tool to meet the PAT initiative of the FDA.

Anwendungsgebiete

+	one measuring system for different cultures (mirco organisms, plantal-, cell cultures, yeast, fungi)
+	substitution of expensive fermentations in stirred bioreactors
+	optimisation of screening conditions in shaken bioreactors
+	non stop applicable (short set-up time)
+	more information about your cultures in shaken bioreactors
+	rapid optimisation of media
+	ensuring a secure scale-up by providing important values (OTR, CTR, RQ, u_max, ...)
+	reduction of the optimisation time and “time to market”
+	reproducible inoculums
+	substitution of long lasting and expensive offline analytics

Bacillus spez.

Botrytis cinerea

Catharanthus roseus

CHO Cells

Corynebacterium glutamicum

Escherichia coli

Gluconobacter oxidans

Hansenula polymorpha

Hybridoma Zellen

Lactobacillus kefir

Nicotiana tabacum

Pichia pastoris

Pichia stipitis

Pseudomonas fluorescens

Pseudoalteromonas haloplanctis

Pseudomonas pudita

Saccharomyces cerevisiae

Streptomyces lividans

Vibrio natregiens

Xanthomonas campestris

RAMOS-Information