CITSens Bio

Product

Online and in-situ measurement of glucose and glutamate

Description

CITSens Bio is a system for online, in situ measurement of glucose and glutamate in cell cultures.

Performance characteristics

 
 
+ Online measurement directly in the culture flasks
+ Monitoring of sterility of the cell cultures and media
+ Optimised cultivation conditions
+ High throughput applications
+ Made for PAT
(process analysis technique)

Recording of measured values in real time

Real time analysis of measurements relevant to the process, takes place in the disposable reactor. This eliminates costly and risky sample taking which disturbs the cell system and could lead to contamination. With CITSens Bio, cell culture sterility is guaranteed at all times.

The CITSens Bio sensor, a screen printed electrode, is very easy to handle. The gamma sterilised sensor is delivered ready for use.

The sensor is connected to the CITSens Bio Beamer by a cable. The CITSens Bio Beamer is placed right next to the reactor system and incorporates a data acquisition unit as well as a transmitter for wireless transmission of the measured values of glucose and glutamate in g/I directly to a receiver. ZOMOFI® receives measurement data from up to 1,000 sensors and transfers these to the PC (RS232 or LAN).

 

tl_files/kuhner/product/shaker/add-ons/Sensor_mit_Deckel_web.jpg

Sensor with cap

Technical data

Online and in-situ measurement of glucose and glutamate

CITSens Bio Sensor

  Screen printed electrode with immobilised enzyme
   
Delivery

gamma sterilised, built into caps of standard disposable bioreactors
Precision

± 1 mmol
Resolution

glucose: 0.1 mmol
glutamate: 0.5 mmol
Detection limit
(glucose, glutamate)
1 mmol
Longest cultivation time
200h
Calibration
2 point calibration in situ
Dimensions
thickness: app. 150 μm
diameter at tip: 1 cm
length: 10cm or 22 cm
(different lengths on request)
Service life in continuous use
14 days
Shelf life
6 months at 5°C

Radio Transmitter CITSens Bio Beamer

   
   
Technology
aktive RFID
Frequency
2.4 - 2.483 GHz
Battery
rechargeable batteries
Dimensions
LxWxH: 85x46x16 [mm]

Radio Receiver ZOMOFI

   
   
Technology
aktive RFID
Frequency
2.4 - 2.483 GHz
Dimensions
LxWxH: 125x107x27 [mm]
Weight
204g
PC-connection
RS232
Network connection with integrated
Lantronix WLAN/LAN module
Software
21CFR11 compliant