Reliability pays

All ISF1-X components are designed for durability and reliability. A Kuhner shaker is a cost effective investment in quality backed with a five year warranty.

A system that grows with your needs

Up to three ISF1-X shaking incubators can be stacked together for greater shaking capacity. Stacking is a simple procedure without the need for special tools or stacking kits. Each machine operates independently and can be equipped with cooling if required. For cell cultivation the ISF1-X is available with CO_2. If using microtiter plates or particularly long cultivation times in shake flasks, the controlled humidity option will help reduce evaporation.

The Kuhner direct drive cannot be matched

The maintenance-free direct drive is both long lasting and economical. The drive is protected from spills and the all stainless steel interior has a drain at the back for quick removal of any unwanted liquids. The incubator chamber can be cleaned with chemicals or sterilized using optional UV lighting. Kuhner’s direct drive system allows the shaking diameter to be changed at any time as well as guaranteeing low energy consumption.

A safe system

An upward opening door fitted with a safety switch, means the ISF1-X is easy to load and unload. Automatic supervision of the mains voltage protects the shaker and in the event of a voltage spike the unit disconnects from the mains. The machine resumes operation at the set values once power is restored.

Innovation Partners

The ISF1-X sets today’s standard for incubator shakers thanks to its technology and functionality. To keep it that way, Kuhner maintains close contact with well-known universities and experts. We constantly investigate new developments looking for opportunities to further optimise the design and performance of our machines.

Dimensions (in mm)

Cooling

All Kuhner incubator shakers can be fitted with cooling. The refrigeration system is regulated by a fully digital PID control ensuring minimal energy consumption. The cooling is switched on only when required as determined by the chamber temperature and set point. 

• Further information can be found under kuhner technology.

Humidity control

Humidity control is an important factor in successful fermentation. Evaporation from microtiter plates, or when cultivating in flasks for long periods (e.g. cell cultures), can be significantly reduced with humidification.

• Further information can be found under kuhner technology.

CO2 control

CO₂ control is essential when working with mammalian cell cultures. Kuhner was the first company to manufacture and supply incubator shakers with CO₂ control more than ten years ago and continues to offer this option.

• Further information can be found under kuhner technology.

Pull-out table

The pull-out table is designed for the ISF1-X and ISF4-X incubator shakers as well as the Rack System. This remarkable device makes loading and unloading trays much easier.

Dual table

The dual table is an easy and economical way of doubling the shaking capacity. The dual shaking table consists of two levels. Each level will accept an E, EX or F size tray. However, with the dual table the shaking speed is limited to a maximum of 200 rpm.

Illumination unit for photosynthesis (LED)

The ceiling of any Kühner incubator shaker can be fitted with LED modules for the cultivation of phototrophic organisms. The control module allows full programming of night/day cycles and variable light intensity.

UV lamp

As in a biological safety cabinet, the chamber of a Kuhner incubator shaker can also be sterilized with an integrated UV lamp. The lamp is situated to maximise irradiation of the chamber and shaking table. The UV lamp has a clearly marked external switch and when the door is opened, the UV-lighting is automatically switched off.

Black window

Available for light sensitive medium or organisms. Any Kuhner incubator shaker can be delivered with blackened windows to prevent unwanted daylight or UV radiation inside the incubator.

Perspex cover

To prevent accidental operation of the controllers, the panel can be protected by a perspex cover.

IQ-OQ Documentation

IQ-OQ (Installation Qualification and Operation Qualification) is an equipment qualification according to GMP procedure. Kuhner offers this service which can also be carried out at the customer’s premises.

BPM-60

BPM-60 (Bioprocess Monitoring) is a non-invasive, online measurement of dissolved oxygen and pH in an Erlenmeyer flask.

Continuous, recording of dissolved oxygen and pH

Dissolved oxygen and pH can be easily measured online using the BPM-60. The system allows for one or both parameters to be recorded in the same flask. The values of dissolved oxygen and/or pH can be monitored simultaneously in eight different flasks.

The continuous data logging, compared to conventional sample taking, is automatic and consistent. The recorded data can be analysed to identify oxygen limitation or inhibition and therefore optimize yields in shaken flasks.

Furthermore, the BPM-60 assists in the production of reproducible starter cultures for use in fermenters (see PAT-initiative of the FDA).

Not on battery mode

An integrated socket at the front of the shaking table makes simple data communication and power supply possible without the risk of wiring breaking. With this technology no battery is required.

ISIS software for data logging

Kuhner ISIS Software is capable of data recording. In addition to logging dissolved oxygen and pH it is also possible to record all other shaker parameters such as shaking speed and CO₂ concentration. A full audit trail is also stored for each shaker connected.

• Further information can be found under add-ons.

Universal tray FU

Order number: SM3003

The universal tray can be fitted with clamps for Erlenmeyer flasks, test tube
holders, microtiter plates, or custom made holders to suit your requirements.
Rearranging these clamps and holders is quick and simple.

• Clamps for Erlenmeyer flasks
• Test tube holders
• High capacity tube holders
• Holders for deep well microtiter plates (Duetz System)
• Sticky mats

F-tray with rubber mat

Order number: SM3603

The whole tray is covered with a rubber mat and is particularly suitable for
shaking containers at low speed (e.g. blood bags).

F-tray with sticky mats

Order number: SM3703

A tray fitted with sticky mats is especially useful for flasks shaken at low speeds (up to <200 rpm). The flask is placed directly on the sticky mat without the need for any other support. Flasks of all sizes can be used. Sticky mats are available individually or in sets and can also be supplied already fitted to a tray. The F-size tray accepts 7 mats.

F-tray with support bars

Order number: SM4130.6

This tray offers an alternative to both clamps and sticky mats and is ideal for tall containers. The tray is covered with a rubber mat and has an upright at each corner. The F-tray is fitted with six cross supports. These support bars securely clamp containers.

F-tray for centrifuge tubes

Order number: SM3805

The use of centrifuge tubes (e.g. 50ml Falcon tubes and TPP 50ml) in cell culture screening is well established. This F-tray has a capacity of 120 x 50 ml centrifuge tubes (5 racks of 24).

Holders for 600ml TPP tubes are also available.

Floor stand

Order numbers: SM1560 (2 x ISF1-X), SM1561 (1 x ISF1-X)

For a comfortable working height Kuhner offers floor stands for both the ISF1-X and LT-X incubator shakers. These are available in a choice of 400mm or 765mm high.

Shelf

Order number: SMX1572

The ISF1-X incubator shakers can be fitted with a shelf allowing cultivation in petri dishes. One or two shelves can be placed above the shaking table and fixed to the chamber walls with four screws.

Water bath

Order numbers: SMX1532 (ISF1-W), SMX1533 (ISF1-X)

To reduce evaporation from shake flasks or microtitre plates a stainless steel water bath can be placed inside the incubator. This water bath is not fitted with an automatic water supply and must be topped up manually.

ISIS-Software

Kuhner developed the user friendly ISIS-Software for supervision, monitoring, and recording of data. The software is easy to operate.

• Further information can be found under kuhner technology.

Interfaces

Kuhner shakers are equipped with a CAN-bus. CAN-USB, CAN-Ethernet, EMI-60 and NET-60 are all well established interfaces.

• Further information can be found under kuhner technology.