BioLector
By combining biochemical engineering, micro system processing and optical sensor know-how, a unique micro fermentation system was developed. Kuhner distributes an automated bench-top cultivation system, which is foreseen to be implemented in standard automated liquid-handling platforms or can be operated manually. The BioLector is originally produced by m2p, Germany.
The main features of the system are:
- high throughput fermentation
(96 reactions at 100-200µl scale)
- non-invasive online analytics
(biomass, NADH, GFP, pH, DO, T)
- scalability to production fermenters
(due to defined engineering parameters in
all scales) |
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Advantages:
- small volumes
- high throughput
- high information content
- easy manual handling
- automation possible
- less effort
- reliable first kinetic fermentation data from microreactors
- defined engineering parameters (OTR,…)
- scalability to lab and production fermentors
- less development cost
- reduced time to market
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Applications:
- cellular screening
- strain selection
- growth activity test
- media optimisation
- fermentation parameter screening
- gene and proteine expression studies
- system biology
- proteomic studies
- inhibition and toxicity tests
- enzyme activity test
- quality control
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