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Comparison

Comparison between a 1L strirred bioreactor and COSBIOS


 
 
 
 
Continuous fermentations of the yeast Saccharomyces cerevisiae were carried out in a 1L stirred bioreactor and with COSBIOS. The results are presented in the following figure. 
 

COSBIOS_Hefe.jpg

The circles represent results gained with COSBIOS, and the squares represent results generated with the 1L stirred bioreactor. Both results are very similar.

The advantages of COSBIOS are obvious, as shown in the following table: 

reactor type

liquid
volume
[mL]

substrate
consumption
[L]

parallel
reactors

duration of
experiment
[d]

COSBIOS 28 9 6 10
1L-Fermenter 1000 316 1 33

 

+ low investment costs
+ at least 6 parallel reactors
+ small liquid volume (tracer
    experiments)
+ six equilibriums states at one
    time

 

Advantages